Sorry, you need to enable JavaScript to visit this website.

RENEW Science

Sculptra aesthetics backed by science


Better understanding the action behind injectable poly-L-lactic acid aesthetic treatments will help you achieve more precise results and exceed patient expectations. 

The action of poly-L-Lactic acid

Sculptra is based on poly-L-Lactic acid (PLLA), a biocompatible, biodegradable material that has been used for many years in dissolvable stitches and implants. When PLLA is injected into the deeper layers of the skin, it helps stimulate the production of collagen. The process begins when PLLA is introduced to the deep dermis or subcutaneous layer, filling out wrinkles and defects. After a few days, the other constituents of the treatment preparation break down and are absorbed by the body, leaving the PLLA particles in place. The body then recruits macrophages to surround the PLLA particles. These fuse to giant cells and recruit fibroblasts. The fibroblasts deposit collagen, which then remains in place to provide long-lasting improvements to wrinkles and volume defects. 
Dr Chris Surek, How do I choose then right treatment for my face?