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REFINE FILL Product Page

Restylane’s complementary technologies help you smooth away wrinkles and folds  

Changes to the underlying structure of the skin over time result in folds and wrinkles that alter the appearance of the face.1 Your patients can feel a disconnect between what their faces express and what they feel. Use the complementary technologies in the Restylane Fill range to smooth away wrinkles and folds.

Featuring Galderma’s NASHA technology, Restylane is the original non-animal stabilized hyaluronic acid filler for wrinkles and lines.2 Restylane Refyne, meanwhile, is formulated using the precision of Optimal Balance Technology. Use it to fill lines and moderate wrinkles for a refined result.

By delivering long-term patient satisfaction3,4,5 our Fill range provides you with the foundation to build relationships – and your practice.

Why Restylane?

Why the Restylane Fill range?

Different patient faces present you with different challenges. That’s why Galderma provides you with two different and complementary injectable technologies in our Restylane Fill range.

Choose from the firmer gel texture of the original Restylane or use the softer gel texture available in Restylane Refyne for a softer look. Each allows you to smooth away wrinkles and folds, helping patients to fight the signs of facial aging.

Restylane hyaluronic acid NASHA gels have a composition closer to natural HA than any other filler.6 The firmer gel quality in Restylane makes it ideal for lifting and precision. Targeted product integration in the tissue helps you to obtain projection and definition.7
  
Restylane Refyne, meanwhile, uses Galderma’s Optimal Balance Technology (OBT) to help you provide a softer look. Developed to complement our NASHA gels, Galderma OBT filler options include softer, more flexible gels thanks to varying degrees of HA cross-linking. Distributed product integration in the tissue allows for contouring and volume.8 Use Restylane Refyne in patients with thinner tissue coverage where a softer product is required.9

Use the Restylane Fill range to build relationships and grow your practice. Restylane delivers results that last up to 18 months with one retreatment.10
 

Lady happy with her treatments from the Restylane Fill range
Treatment areas

WHERE TO USE THE RESTYLANE FILL RANGE

Use both Restylane and Restylane Refyne for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds.

Nasolabial folds
Marionette lines
Upper lip lines
Lips
Tear trough

WHERE TO USE THE RESTYLANE FILL RANGE

Nasolabial folds
Nasolabial folds
Upper lip lines
Lips
Tear trough

Use both Restylane and Restylane Refyne for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds.

Techniques

Precision through technique

The world’s best aesthetic clinicians keep on learning throughout their careers. Your expertise at using Restylane Fill products will increase through repeated use and by thoroughly understanding the correct injection points.
The world’s broadest portfolio of injectable technologies
The Science

The science behind Restylane Fill products

Every product that Galderma sells and every claim we make is backed up by solid science. Better understanding of the action behind Restylane Fill products will help you achieve more precise results and deliver high patient satisfaction.
 Pioneering science in aesthetics medicine

BEFORE AND AFTER

Featuring two complementary technologies, Restylane’s Fill range is a favorite with healthcare professionals looking to build patient relationships. 

Before & After

Catherine_BEFORE
Ninorta_BEFORE
Jean-Paul_Pietrus_BEFORE
Christina_BEFORE
Vanessa_Samuels
Cassandra_Valborg_BEFORE
Irina_Sagtegen_BEFORE
Jessica_BEFORE
Shahrul_BEFORE
Sibel_Ama_BEFORE
Jenny_Sheleby_BEFORE
Jenny_Sheleby_Decolletage_BEFORE
Katriina_BEFORE
Rafat_Klan_BEFORE
Kathy_Chan_BEFORE
Maria_BEFORE
Sofia_BEFORE
Yohan_Vandemberg_BEFORE
Catherine_BEFORE
Ninorta_BEFORE
Jean-Paul_Pietrus_BEFORE
Christina_BEFORE
Vanessa_Samuels
Cassandra_Valborg_BEFORE
Irina_Sagtegen_BEFORE
Jessica_BEFORE
Shahrul_BEFORE
Sibel_Ama_BEFORE
Jenny_Sheleby_BEFORE
Jenny_Sheleby_Decolletage_BEFORE
Katriina_BEFORE
Rafat_Klan_BEFORE
Kathy_Chan_BEFORE
Maria_BEFORE
Sofia_BEFORE
Yohan_Vandemberg_BEFORE
Before Catherine_BEFORE
After Catherine_AFTER
Caption

Botulinum toxin

Restylane fillers

Before Ninorta_BEFORE
After Ninorta_AFTER
Caption

Botulinum toxin

Restylane fillers

Before Jean-Paul_Pietrus_BEFORE
After Jean-Paul_Pietrus_AFTER
Caption

Restylane fillers

Before Christina_BEFORE
After Christina_AFTER
Caption

Botulinum toxin

Restylane fillers

Before Vanessa_Samuels
After Vanessa_Samuels_AFTER
Caption

Restylane fillers

Before Cassandra_Valborg_BEFORE
After Cassandra_Valborg_AFTER
Caption

Restylane fillers

Before Irina_Sagtegen_BEFORE
After Irina_Sagtegen_AFTER
Caption

Restylane fillers

Before Jessica_BEFORE
After Jessica_AFTER
Caption

Restylane fillers

Before Shahrul_BEFORE
After Shahrul_AFTER
Caption

Restylane fillers

Before Sibel_Ama_BEFORE
After Sibel_Ama_AFTER
Caption

Restylane fillers

Before Jenny_Sheleby_BEFORE
After Jenny_Sheleby_AFTER
Caption

Restylane fillers;

Restylane Skinboosters

Before Jenny_Sheleby_Decolletage_BEFORE
After Jenny_Sheleby_Decolletage_AFTER
Caption

Restylane Skinboosters

Before Katriina_BEFORE
After Katriina_AFTER
Caption

Restylane Skinboosters

Before Rafat_Klan_BEFORE
After Rafat_Klan_AFTER
Caption

Restylane Skinboosters

Before Kathy_Chan_BEFORE
After Kathy_Chan_AFTER
Caption

Botulinum toxin; Restylane fillers

Before Maria_BEFORE
After Maria_AFTER
Caption

Botulinum toxin;

Restylane fillers

Before Sofia_BEFORE
After Sofia_AFTER
Caption

Botulinum toxin;

Restylane fillers

Before Yohan_Vandemberg_BEFORE
After Yohan_Vandemberg_AFTER
Caption

Botulinum toxin;

Restylane fillers

Why physicians choose Galderma
A choice of two complementary technologies
Smooth away wrinkles and folds

Long-term patient satisfaction3,4,5 to help build relationships – and your practice

Our broad portfolio of products

Use the products in Galderma’s complementary range of aesthetic solutions alone or in combination to create the right result for every individual.

Relaxed beautiful smiling woman treated with botulinum toxin, find dermatologist near you. Galderma.
RELAX
Relax facial muscles associated with frown lines and crow's feet to temporarily improve moderate to severe glabellar lines (frown lines) and lateral canthal lines (crow’s feet lines).
REFRESH
Refresh your skin from within with a boost of deep hydration, for a refreshed and vibrant look that lasts.
Sculptra activate the power of your skin
RENEW
Renew the structure of your skin with a collagen activator that gradually builds the foundation of the youthful, firmer you. 

REFERENCES

  1. Finn CJ et all. Dermatol Surg 2003;29(5):450-455
  2. Data on file (MA-39680).
  3. Talarico S et al. Dermatol Surg 2015;41:1361–1369
  4. Cartier H et al. J Drugs Dermatol 2012;11(1 Suppl):s17–26 
  5. Philipp-Dormston et al. Dermatol Surg 2018;44(6):826–832
  6. Kablik J et al. Dermatol Surg 2009;35(Suppl1):302–312.
  7. Data on file (MA-33947).
  8. Segura S et al. J Drugs Dermatol 2012;11(1 Suppl:s5–8).
  9. Philipp-Dormston WG et al. Dermatol Surg 2018;44(6):826-832.
  10. Narins RS et al. Dermatol Surg 2008;34:S2–S8