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RELAX Science

How does botulinum toxin work

The science behind botulinum toxin 

Every product that Galderma sells and every claim we make is backed up by solid science. Better understanding the action behind botulinum toxin will help you achieve more precise results and exceed patient expectations. 

Targeted neurotransmitter blocking

Botulinum toxin is a naturally occurring substance produced by Clostridium botulinum.1 When injected, the toxin works as a muscle relaxant, temporarily weakening the activity of targeted muscles. It achieves this by blocking the transport of the neurotransmitter acetylcholine across the neuromuscular junction, located between the nerve end and the muscle fiber.

The mode of action of botulinum toxin involves four main stages, all of which must function correctly for activity to occur. The effects of botulinum toxin last until the junction has recovered and muscle activity returns.2



  1. Poulain B et al. Botulinum J. 2008;1:14-87
  2. Azzalure SmPc